Manchester has its own airport located south of the city. It can be reached from Manchester Piccadilly railway station by fast train or by using the slower Metrolink tram system.
Manchester Airport has its own railway station and is only 15-20 minutes from the city centre by direct rail link. There is a good choice of flights here including British Airways, Easyjet and Ryanair.
London Heathrow can be reached by rail via London Paddington or by direct coach service. London Gatwick can be reached by rail via London King's Cross or by direct coach too.
National Express provides coach services between all major cities and airports in the UK. Prices are variable with the easiest booking available online. Airport services are usually more expensive. Tickets are for a specific journey only.